Microbial dysbiosis and carcinogenesis: Exploring the contribution of the microbiome to major human cancers

Asma Mohammadizade

doi:10.66224/jcbior.7.1.347

Authors

Asma Mohammadizade Department of Microbiology, Faculty of Sciences, Kerman Branch, Islamic Azad University, Kerman, Iran https://orcid.org/0009-0008-7795-1097

DOI:

https://doi.org/10.66224/jcbior.7.1.347

Keywords:

Microbiota, Dysbiosis, Carcinogenesis, Metabolites

Abstract

Scientific progress has greatly enhanced our understanding of the complex link between cancer and the microbiome. Research suggests that the way the human body interacts with its microbial communities is a key factor in maintaining health and in the development of disease. The human microbiome has numerous benefits, including the Regulation of essential processes such as immune signaling and metabolism, which contribute to the proper functioning of the host. Microbiota imbalance is associated with the development and progression of cancer. This review article aims to investigate the microbiome's effect on the development and progression of cancer, which could lead to significant progress in the prevention, diagnosis, and treatment of this cancer. Overall, further studies are needed to provide new insights into the diagnosis, prevention, and treatment of cancer. Also, the design of clinical research related to the interaction of the microbiome genome and the human host genome could be of interest, and signaling pathways involved in disease.

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